目的 评估早产儿发生低血糖的危险因素，以期为其血糖管理提供依据。 方法 回顾性分析2019年1-12月入住某院新生儿重症监护室的胎龄＜37周的早产儿的临床资料，其中以血糖＜2.2 mmol/L为低血糖组，血糖正常者为正常组，分析筛选早产儿低血糖的危险因素。 结果 两组早产儿在出生体重、分娩方式、是否为小于胎龄儿（small for gestational age infant，SGA）及孕母是否存在高血压、妊娠期糖尿病、妊娠期甲状腺功能减退等因素上的差异均有统计学意义（均P＜0.05）。SGA（OR=1.579）、妊娠期高血压（OR=1.872）、妊娠期糖尿病（OR=2.937）和妊娠期甲状腺功减退（OR=1.727）是早产儿低血糖的独立危险因素（均P＜0.05），顺产（OR=0.509）是其保护因素（P＜0.05）。 结论 临床上应加强SGA和孕母存在妊娠期高血压、妊娠期糖尿病、妊娠期甲状腺功能减退的早产儿的血糖管理，以防止低血糖的发生。

Objective To evaluate the risk factors of hypoglycemia in premature infants,so as to provide basis for the management of hypoglycemia in premature infants. Methods Retrospective study was conducted among the neonates whose gestational age was less than 37 weeks and who were admitted to the neonatal intensive care unit from January to December 2019.The hypoglycemic group was defined as those whose blood glucose was lower than 2.2 mmol/L,and the normal group was randomly selected as the premature infants whose blood glucose was monitored in the same period.The risk factors of hypoglycemia in premature infants were screened and analyzed. Results There were significant differences in birth weight,delivery mode,small for gestational age infant（SGA） or not,pregnancy-induced hypertension,pregnancy-induced diabetes,and pregnancy-induced hypothyroidism between the two groups (all P＜0.05).SGA (OR=1.579),pregnancy-induced hypertension (OR=1.872),pregnancy-induced diabetes (OR=2.937) and pregnancy-induced hypothyroidism (OR=1.727) were independent risk factors for hypoglycemia in preterm infants (all P＜0.05),and spontaneous delivery (OR=0.509) was protective factors for hypoglycemia in preterm infants (P＜0.05). Conclusion SGA,pregnancy-induced hypertension,pregnancy-induced diabetes,and pregnancy-induced hypothyroidism can increase the risk of hypoglycemia in preterm infants,which should be paid attention to in clininal nursing.

R473.72