目的 总结患者家属ICU后综合征（post-intensive care syndrome-family，PICS-F）心理功能障碍的发生率和危险因素,为早期发现、早期干预提供理论依据。 方法 检索Embase、PubMed、Cochrane library、EBSCO、Web of Science、中国生物医学数据库、知网、万方、维普等数据库，检索时限从建库至2022年5月，纳入关于PICS-F心理功能障碍发生率及危险因素的文献，并进行分析。 结果 共纳入16篇文献（10 756名研究对象），PICS-F心理功能障碍发生率为28%。患者年龄≤65岁(OR=1.06)、患者入住ICU＞6 d(OR=4.72)、APACHE Ⅱ评分高(OR=5.95)、患者死亡(OR=1.90)、家属为女性(OR=4.07)、家属为配偶(OR=2.24)、家属有心理疾病史(OR=3.77)、家属学历为中学水平以下(OR=1.07)是PICS-F发生的危险因素。 结论 临床医护人员除关注患者本身外，还应该针对以上高危人群的心理状态进行早期干预，避免PICS-F心理功能障碍的发生 。

Objective To summarize the incidence and risk factors of psychological dysfunction in patients’ families suffering from post-intensive care syndrome-family(PICS-F),and to provide theoretical basis for early detection and early intervention. Methods The databases including Embase,PubMed,Cochrane library,EBSCO,Web of Science,China Biomedical Database,CNKI,Wanfang,and VIP were systematically searched.The search period was from the inception to May 2022.The literature on the risk factors of psychological dysfunction were included and analyzed. Results A total of 16 literatures (10 756 subjects) were included,and the incidence of psychological dysfunction of PICS-F was 28%.Patient age ≤65 years old (OR=1.06),patient admitted to ICU ＞6 days (OR=4.72),APACHE high score of Ⅱ (OR=5.95),death of the patient (OR=1.90),female family members(OR=4.07),spouse (OR=2.24),history of mental illness (OR=3.77),and education level below secondary school level (OR=1.07) were the risk factors for PICS-F. Conclusions Clinical medical staff should not only pay attention to the patients themselves,but also conduct early intervention according to the psychological state of the above high-risk groups,so as to avoid the occurrence of PICS-F psychological dysfunction.

R473.54

江西省教育厅科学技术研究项目(GJJ160140)