目的 探讨重症监护病房(intensive care unit,ICU)儿童氧合状态与谵妄发作之间的关系。 方法 2021年10月至2022年3月，方便抽样法选取某三级甲等医院289例ICU儿童为研究对象，收集患儿氧合状态等相关临床资料，采用躁动镇静量表和康奈尔儿童谵妄评估量表对其进行调查。 结果 ICU儿童谵妄发生率为34.3%。Spearman相关分析显示，氧合状态与谵妄发作呈负相关(P＜0.001)。Logistic回归分析结果显示：年龄、胎龄、感染、肾功能异常、镇静药物及氧合状态受损是ICU儿童谵妄发作的主要影响因素(均P＜0.05)；氧合状态受损严重程度每增加一个等级，谵妄发作风险增加2.47倍(P＜0.001)。 结论 ICU儿童氧合状态越差，越容易发生谵妄。医护人员应加强对患儿氧合状态的监测并及时采取针对性干预措施，积极纠正氧合状态受损，从而降低谵妄发生率。

Objective To investigate the correlation between oxygenation state and delirium among pediatric patients in Intensive Care Unit(ICU). Methods The convenience sampling method was used to select 289 pediatric patients in ICU in a tertiary A hospital from October 2021 to March 2022.Oxygenation state and other clinical data were collected.Richmond agitation-sedation scale(RASS) and Cornell assessment of pediatric delirium scale(CAPD) were used for investigation. Results Among the 289 subjects,the incidence of delirium was 34.3%.Spearman correlation analysis showed that oxygenation state was negatively correlated with delirium onset(P＜0.001).Logistic regression analysis showed that age,gestational,infection,renal dysfunction,sedation and impaired oxygenation state were the main influencing factors of delirium(all P＜0.05) The risk of delirium increased by 2.47 times for each increased grade of severity of impaired oxygenation(P＜0.001). Conclusions The worse the oxygenation state of pediatric patients in ICU,the more likely the delirium occurs.Nurses should strengthen the monitoring of oxygenation state and take timely targeted intervention measures to actively correct the impairment of oxygenation state,so as to reduce the incidence of delirium.

R473.72

上海市科委基金项目资助（21511100502）