[关键词]
[摘要]
目的 系统评价老年人围术期睡眠障碍与术后谵妄发生风险的关系。 方法 计算机检索Pubmed、Embase、Web of Science、Cochrane Library、CNKI、Wanfang、VIP和Sinomed等数据库中有关老年人围术期睡眠障碍与术后谵妄发生风险关系的相关文献,搜索时间为建库至2022年3月。采用Revman 5.3软件进行Meta分析。 结果 共纳入17项研究,涉及5396名患者。Meta分析结果显示,老年人围术期睡眠障碍会增加术后谵妄的发生风险[OR=3.29,95%CI(2.36,4.58),P<0.001]。亚组分析显示,不同研究设计类型、睡眠障碍类型、睡眠障碍发生时间、手术类型、谵妄评估工具均与术后谵妄的发生风险均密切相关。 结论 医务人员应重视老年人围术期睡眠障碍对术后谵妄的影响,加强管理和预防。
[Key word]
[Abstract]
Objective To systematically evaluate the relationship between perioperative sleep disorders and the risk of postoperative delirium among the elderly. Methods Literature on the relationship between perioperative sleep disorders and the risk of postoperative delirium among the elderly was searched by computer from Pubmed,Embase,Web of Science,Cochrane Library,CNKI,Wanfang,VIP and Sinomed databases.The retrieval period was from the inceptions to March 2022.Meta-analysis was performed using Revman 5.3 software. Results A total of 17 studies were included,with a total sample size of 5 396 patients.Meta-analysis showed that sleep disorders was significantly correlated with postoperative delirium among the elderly[OR=3.29,95%CI(2.36,4.58),P<0.001].Subgroup analysis showed that different study designs,different types of sleep disorders,different onset time of sleep disorders,different types of surgery,and different delirium assessment tools were significantly correlated with the risk of postoperative delirium. Conclusions Medical staff should pay attention to the influence of perioperative sleep disorders on postoperative delirium among the elderly,and strengthen the management and prevention.
[中图分类号]
R473.59;R47-05
[基金项目]
国家科技部“主动健康和老龄化科技应对”重点专项(2020YFC2003104)