目的检索、评价并汇总国内外关于胰腺癌新辅助治疗患者术前营养管理的最佳证据，为胰腺癌新辅助治疗患者开展术前营养实践提供依据。方法系统检索各指南网站及中英文数据库有关胰腺癌新辅助治疗患者术前营养的相关指南、专家共识、系统评价等,证据检索时间为建库至2023年5月。结果共纳入文献10篇，其中专家共识6篇、指南2篇、系统评价2篇,总结出围绕组建团队、营养培训、营养筛查与评定、营养干预、随访评价、健康教育等6个方面的18条证据。结论医护人员应重视胰腺癌新辅助治疗患者术前营养状态，可以根据患者的医院、临床情景结合最佳证据为患者制订个体化的营养干预方案，规范营养管理流程，改善术前营养状态，降低术后并发症的发生。

Objective To search,assess and summarize the best evidence for preoperative nutritional management in patients undergoing neoadjuvant therapy for pancreatic cancer,and to provide a basis for preoperative nutritional practice in patients with neoadjuvant therapy for pancreatic cancer.Methods The best evidence of the preoperative nutritional management of pancreatic cancer patients with neoadjuvant therapy were searched systematically,including relevant guidelines,expert consensuses,and systematic reviews.The retrieval period was from the inceptions to May 2023.Results A total of 25 articles were included,with 6 expert consensus,2 guidelines and 2 systematic reviews.A total of 18 best evidences in 6 aspects were summarized,namely team building,nutrition training,nutrition screen and assessment,nutrition intervention,follow-up evaluation and health education.Conclusions Medical staff should pay attention to the preoperative nutritional status of patients with neoadjuvant pancreatic therapy,and can formulate individualized nutritional intervention plans for patients according to the hospital and clinical situation of patients and combined with the best evidence,standardize the nutritional management process,improve the preoperative nutritional status,and reduce the occurrence of postoperative complications.

R473.6

复旦大学循证护理中心证据转化与临床应用项目（Fudanebn202336）；浙江省医药卫生科技项目（2022KY819）