目的 基于主客体互倚模型探讨宫颈癌化疗患者夫妻二元应对水平、婚姻调适与生活质量的关系，为临床干预提供理论依据。方法 2021年8月至2022年9月，采用便利抽样法选取在郑州市某三级甲等医院妇科和肿瘤科住院治疗的180对宫颈癌化疗患者夫妻为研究对象。采用二元应对量表、婚姻调适量表和生活质量量表对其进行调查。结果 宫颈癌患者的二元应对、婚姻调适与生活质量得分均低于其配偶，差异均有统计学意义（均P＜0.05）。宫颈癌患者及配偶的二元应对、婚姻调适与生活质量均呈正相关（均P＜0.05）。在主体效应方面，宫颈癌患者夫妻的二元应对及婚姻调适均能够预测自身的生活质量，呈正相关（β=0.678、0.62、0.65、0.64,P＜0.001）；在客体效应方面，患者二元应对及婚姻调适能够预测配偶的生活质量，配偶的二元应对及婚姻调适也能预测患者的生活质量，均呈正相关（β=0.62、0.597、0.600、0.675,P＜0.001）。结论 宫颈癌化疗患者的生活质量不仅受自身影响，也受配偶的影响，要重视患者夫妻的二元应对水平和婚姻调适的交互影响，从而改善宫颈癌患者夫妻的生活质量。

Objective To explore the relationship among dyadic coping,marital adjustment and quality of life in patients with cervical cancer undergoing chemotherapy based on the actor-partner interdependence model,so as to provide a theoretical basis for clinical intervention.Methods A total of 180 couples of patients with cervical cancer who were hospitalized in gynecology and oncology departments of a tertiary A hospital in Zhengzhou from August 2021 to September 2022 were selected by convenience sampling method.Dyadic Coping Inventory,Locke-Wollance Marital Adjustment Test and the Short-Form 36 Health Survey Scale were used to investigate the subjects.Results The scores of dyadic coping,marital adjustment and quality of life of cervical cancer patients were lower than those of their spouses,with statistical significance differences(P＜0.05).The quality of life was positively correlated with dyadic coping and marital adjustment of cervical cancer patients and their spouses (all P＜0.05).In terms of subjective effect,the dyadic coping and marital adjustment of cervical cancer patients could predict their own quality of life,and were positively correlated (β=0.678,0.62,0.65,0.64,P＜0.001)；in terms of object effects,patients’ dyadic coping and marital adjustment could predict spouse’s quality of life,and spouses’ dyadic coping and marital adjustment could also predict patients’ quality of life,all of which were positively correlated (β=0.62,0.597,0.600,0.675,P＜0.001).Conclusions The quality of life of cervical cancer patients undergoing chemotherapy is not only affected by themselves,but also by their spouses.It is necessary to pay attention to the interaction between dyadic coping level and marital adjustment of patients and their spouses,so as to provide a theoretical basis for improving the quality of life of cervical cancer patients and their spouses.

R473.2

河南省医学科技攻关计划项目（LHGJ20200035）