总结国内首次儿童一站式异体嵌合抗原受体T细胞治疗桥接异基因造血干细胞移植的护理经验，旨在为此类治疗提供临床借鉴意义。护理要点包括多团队制订预见性治疗护理方案;精准管理细胞因子释放综合征；评估与护理多部位出血；预防与管理急性移植物抗宿主病；全程预防与护理感染；管理与长期随访营养状况。经过系统诊治与精细化护理，患儿顺利完成该复杂的方案，最终治疗相关并发症得到控制，原发病缓解，移植成功。患儿住院61 d后顺利出院；随访9个月，情况良好。

To summarize the nursing experience of the first pediatric patient undergoing one-stop allogeneic CAR-T therapy bridging hematopoietic stem cell transplantation in China,and to provide clinical reference for such treatment.Key points of nursing care included development of an anticipatory care plans by multi-team,accurate management of cytokine release syndrome,assessment and nursing of multi-site bleeding,prevention and management of acute graft-versus-host disease,whole-process prevention and nursing of infection;nutrition support and long-term follow-up.After systematic diagnosis,treatment and fine nursing,the patient successfully completed the complex program,and finally the treatment-related complications were controlled,the primary disease was alleviated,and the transplant was successful.The patient was discharged successfully after 61 days in hospital.The follow-up was good for 9 months.

上海申康医院发展中心临床三年行动计划资助（SHDC2023CRS010）；上海市抗癌协会肿瘤护理专委会“护航”计划（SACA-HH202111）