目的 调查脑卒中患者复发恐惧潜在剖面及影响因素，为制订个体化的复发恐惧管理方案提供依据。方法 2023年11月至2024年1月，采用便利抽样法选取浙江省某三级甲等医院脑卒中患者500例为研究对象，采用恐惧疾病进展简化量表、经济毒性综合评分量表、多伦多述情障碍量表-20、脑卒中特定生存质量量表等对其调查并进行潜在剖面分析，运用单因素分析及Logistic回归分析不同剖面的影响因素。结果 脑卒中患者的疾病复发恐惧评分为（38.96±13.60）分，约66.8%的患者存在复发恐惧。经济毒性、述情障碍、生活质量评分分别为（31.14±7.13）分、（67.26±12.23）分和（170.14±41.47）分。患者的疾病复发恐惧情况可分为低复发恐惧-稳定组（36.6%）、中复发恐惧-依从组（33%）和高复发恐惧-依赖组（30.4%）3个剖面类型。单因素分析显示，不同潜在剖面在年龄、家庭月均收入、脑卒中类型、营养供给情况、经济毒性等项目上的差异均有统计学意义（均P＜0.05）。Logistic回归分析显示，家庭月收入、文化程度、婚姻状况、脑卒中类型、经济毒性、生活质量是脑卒中患者复发恐惧的影响因素（均P＜0.05）。结论 脑卒中患者复发恐惧具有群体异质性，应针对每种类别给予个体化护理干预。

Objective To analyze the potential profile and influencing factors of fear of recurrence in stroke patients and to provide the basis for formulating individual recurrence fear management program.Methods The convenience sampling method was used to select 500 stroke patients who were admitted to a tertiary A hospital in Zhejiang Province from November 2023 to January 2024.A survey was conducted using Fear of Progression Questionnaire-Short Form,Comprehensive Scores for Financial Toxicity Based on the Patient-Reported Outcome Measures，twenty-item Toronto alexithymia scale,and Stroke-Specific Quality of Life Scale to investigate the potential profile analysis.Univariate analysis and logistic regression analysis were used to identify the influencing factors of the potential profile.Results The recurrence fear score of stroke patients was(38.96±13.60),and about 66.8% of patients had recurrence fear.Economic toxicity,alexithymia and quality of life scores were(31.14±7.13) points,(67.26±12.23) points and(170.14±41.47) points,respectively.The patients’ fear of relapse could be divided into three profile types:low fear of relapse-stable group(36.6%),medium fear of relapse-compliance group(33%) and high fear of relapse-dependence group(30.4%).Univariate analysis showed that different potential profiles had statistically significant differences in age,mean monthly family income,stroke type,nutritional supply,economic toxicity and other items(all P＜0.05).Logistic regression analysis showed that monthly family income,educational level,marital status,stroke type,economic toxicity and quality of life were the influencing factors of relapse fear in stroke patients(all P＜0.05).Conclusions The fear of relapse in stroke patients has population heterogeneity,and individual nursing intervention should be given for each category.

R473.74

浙江省医药卫生科技计划项目（2022KY766）