目的 通过Meta分析明确缺血性脑卒中后情感淡漠的影响因素，为制订针对性的干预措施提供可靠依据。 方法 计算机检索中国知网、万方、维普、PubMed、Embase、Web of Science等数据库，收集与缺血性脑卒中后情感淡漠相关的文献，并采用RevMan 5.4软件进行Meta分析。 结果 共纳入21篇文献，包含20项研究，涉及3074例研究对象，提取到28个影响因素。结果显示，年龄、受教育程度、脑卒中史、C反应蛋白、血浆同型半胱氨酸、低密度脂蛋白、纤维蛋白原、认知功能、脑卒中严重程度、日常生活能力、抑郁、痴呆等是缺血性脑卒中后情感淡漠的主要影响因素（均 P ＜0.05）。 结论 缺血性脑卒中后情感淡漠受多种因素综合影响，护理人员可根据这些影响因素识别高风险患者群体，并提供针对性干预，以改善患者预后。

Objective To conduct a meta-analysis to clarify the influencing factors of apathy after ischemic stroke，so as to provide a reliable basis for the development of targeted intervention measures.Methods CNKI，Wanfang，VIP，PubMed，Embase，and Web of Science were searched for studies on apathy after ischemic stroke.RevMan 5.4 was used for Meta-analysis.Results A total of 21 articles were included，encompassing 20 studies with 3074 subjects，and 28 influencing factors were extracted.Results showed that age，education level，stroke history，C-reactive protein，plasma homocysteine，low density lipoprotein，fibrinogen，cognitive function，stroke severity，ability of daily living，depression，and dementia are influencing factors of apathy after ischemic stroke(allP ＜0.05).Conclusions Apathy after ischemic stroke is influenced by a variety of factors.Nurses can identify high-risk patient groups for apathy based on these influencing factors，provide targeted interventions，and improve patient outcomes.

R473.74

国家自然科学基金青年项目（72204066）