目的 探讨疾病感知在青年乳腺癌患者心理资本和疾病接受度间的中介作用。 方法 便利抽样法选取郑州市某三级甲等医院住院的214例青年乳腺癌患者为研究对象，采用中文版疾病接受度量表、简化版疾病感知问卷、积极心理资本问卷等对其进行调查，构建并检验中介模型。 结果 青年乳腺癌患者的心理资本、疾病感知、疾病接受度得分分别为（118.11±17.46）分、（43.25±8.39）分、（21.25±5.79）分。心理资本与疾病接受度呈正相关、与疾病感知呈负相关，疾病感知与疾病接受度呈负相关（均P＜0.01）。疾病感知在心理资本与疾病接受度间起部分中介作用（β=0.274），中介效应占比45.0%。 结论 心理资本可通过疾病感知影响青年乳腺癌患者的疾病接受度。护理人员应采取积极措施增强患者的心理资本，降低其消极的疾病感知，以提高疾病接受度。

Objective To explore the mediating effect of illness perception between psychological capital and acceptance of illness in young breast cancer patients.Methods 214 young breast cancer patients hospitalized in a tertiary A hospital in Henan province were selected by convenience sampling,with data collected by acceptance of illness scale,brief illness perception questionnaire,and positive psychological capital questionnaire,with a mediation model constructed and validated.Results The mean scores of psychological capital,illness perception,and acceptance of illness among young breast cancer patients were (118.11±17.46),(43.25±8.39),and (21.25±5.79),respectively.Psychological capital was positively correlated with acceptance of illness and negatively correlated with illness perception;illness perception was negatively correlated with acceptance of illness (all P＜0.01).Illness perception served as a mediating variable between psychological capital and acceptance of illness (β=0.274),with its mediating effect accounting for 45.0% of the total effect.Conclusions Psychological capital can influence the acceptance of illness through illness perception.Clinical nurses should take active measures to improve the level of psychological capital and mitigate negative illness perception of these patients,so as to improve their acceptance of illness.

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河南省医学科技攻关计划省部共建项目（SB201901067）；河南省中原医创基金会医院管理研究项目（23YCG2005）