目的 系统评估辅助生殖技术（assisted reproductive technology，ART）助孕患者的睡眠障碍发生率，为制订睡眠管理方案提供循证依据。 方法 检索中国知网、万方、PubMed、Embase等10个中英文数据库，收集研究ART助孕患者的睡眠障碍的相关文献，检索时间建库至2025年3月。应用Stata 17.0软件对纳入文献进行Meta分析。 结果 共纳入26篇研究，11 480例研究对象。ART助孕患者睡眠障碍发生率为40%[95%CI(34%~47%）]。亚组分析结果显示：研究发表年份为2020-2025年、男性、女性≥35岁、欧洲、华北和西南地区、接受妊娠试验时、重复助孕周期、有焦虑及抑郁症状时的睡眠障碍发生率更高（均P＜0.001）。 结论 ART助孕患者睡眠障碍发生率较高，需重视和早期评估其睡眠障碍并干预，以改善睡眠质量和助孕结局。

Objective To systematically assess the prevalence of sleep disorders among patients undergoing assisted reproductive technology (ART),and to provide evidence-based support for sleep management plans formulation.Methods Studies on sleep disorders in patients undergoing ART in 10 databases including CNKI,Wanfang,PubMed,Embase,etc.were retrieved from the inceptions to March 2025.Meta-analysis of the included literature was conducted using Stata 17.0 software.Results A total of 26 studies were included,involving 11,480 research subjects.The prevalence of sleep disorders in patients undergoing ART was 40%[95%CI(34%,47%)].The results of subgroup analysis showed that the incidence of sleep disorders was higher in the years of study publication from 2020 to 2025,in men and women aged ≥35 years,in Europe,North China and Southwest China,during pregnancy tests,during repeated assisted reproductive cycles,and when there were anxiety and depression symptoms(P＜0.001).Conclusions The prevalence of sleep disorders among patients undergoing ART is high.Early assessment and intervention are crucial to improve sleep quality and ART outcomes.

R472;R47-05

国家重点研发计划（2022YFC2702903）； 上海市护理学会科研课题重点项目（2022SD-B02）