目的 检索、评价并总结肿瘤治疗相关心血管毒性风险患者运动干预的最佳证据。方法 检索国内外专业网站及数据库中肿瘤治疗相关心血管毒性风险患者运动干预的相关证据，检索时限为2014年1月至2025年12月。由2名研究者分别进行文献质量评价，证据提取和汇总。结果 共纳入文献18篇，其中循证指南3篇、共识性指南及专家共识2篇、证据总结1篇、系统评价11篇及Meta分析1篇。从运动认知、运动获益、风险评估与安全管理、运动方案制订原则、运动参数、运动禁忌及终止、运动方案等7个方面总结34条证据，其中22条证据为1级证据。结论 本研究证据能够为临床医护人员制订肿瘤治疗相关心血管毒性风险患者运动干预方案和开展相关循证实践提供理论依据。

Objective To retrieve,evaluate,and summarize the best evidence of exercise interventions for patients with cancer at risk of cancer therapy-related cardiovascular toxicity(CTR-CVT).Methods Relevant evidence on exercise interventions for patients at risk of CTR-CVT was retrieved from professional websites and databases in China and abroad,with the search period from January 2014 to December 2025.2 researchers independently conducted literature quality evaluation,evidence extraction,and summary.Results A total of 18 articles were included,consisting of 3 evidence-based guidelines,2 consensus guidelines and expert consensuses,1 evidence summary,11 systematic reviews,and 1 Meta-analysis.A total of 34 pieces of evidence were summarized from 7 aspects:exercise awareness,exercise benefits,risk assessment and safety management,principles of exercise program formulation,exercise parameters,exercise contraindications and termination,and exercise program,among which 22 pieces were level 1 evidence.Conclusions This evidence can provide a theoretical basis for clinical medical staff to develop exercise intervention programs for patients with cancer at risk of CTR-CVT, and carry out relevant evidence-based practices.

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山西省大健康产业高质量发展科研专项课题（DJKZXKT2023144）；复旦大学循证护理中心证据转化与临床应用（Fudanebn202402）