目的 调查精神分裂症患者经济毒性的现状,并分析其影响因素。方法 采用便利抽样法选取在大庆市某三级甲等精神专科医院住院的225例精神分裂症患者为研究对象,采用一般资料调查表、患者报告结局的经济毒性综合评分量表、家庭亲密度和适应性量表、社会支持评定量表、阳性与阴性症状量表对其进行调查。结果 精神分裂症患者的经济毒性得分为(21.45±9.28)分。多元线性回归显示,复发次数、职业、家庭人均月收入、家庭功能、症状严重程度、社会支持和享有补贴项数是精神分裂症患者经济毒性的影响因素(均P<0.05)。结论 精神分裂症患者经济毒性较重,精神科医护人员应重点关注症状严重、复发次数多、在职、无业和收入低的患者,通过改善家庭功能,提升社会支持和补贴参与度,降低其经济毒性。

Objective To investigate the current status of financial toxicity in patients with schizophrenia and analyze its influencing factors.Methods A convenience sampling method was used to select 225 inpatients with schizophrenia from a tertiary A psychiatric hospital in Daqing.Data were collected using a general information questionnaire,comprehensive scores for financial toxicity based on the patient-reported outcome measures(COST-PROM),family adaptability and cohesion evaluation scale(FACES),social support rating scale(SSRS),and positive and negative symptom scale(PANSS).Results The financial toxicity score of patients with schizophrenia was (21.45±9.28).Multiple linear regression showed that the number of relapses,occupation,average monthly household income per capita,family functioning,symptom severity,social support,and number of subsidies received were influencing factors of financial toxicity in patients with schizophrenia (all P<0.05).Conclusions Patients with schizophrenia experience severe financial toxicity.Psychiatric healthcare providers should focus on patients with severe symptoms,high relapse frequency,those who are employed or unemployed,and those with low income,and reduce their financial toxicity by improving family functioning and enhancing social support and subsidy participation.

R473.74

国家自然科学基金项目(72204068,72304076,72574006)；黑龙江省省属高等学校基本科研业务费基础研究项目(JQN202103)；教育部人文社科规划项目(24YJAZH005)